qMRI - Quantitative Magnetic Resonance Imaging   2018

‘The pre-eminent role of imaging now requires a new level of metric - quantitative measurements’
Robert I Grossman MD, Chair of Radiology, New York University


New 2018 edition:

Quantitative MRI of the brain: principles of Physical measurement
edited by Mara Cercignani, Nicholas Dowell and Paul Tofts   
hardback:  ISBN:
978-1138032859;  published by CRC press 2018; list price £140; Amazon price £120


"Upon its release in 2003, Paul Tofts’ 'Quantitative MRI of the Brain' instantly became a classic among MR textbooks as it comprised the up-to-then knowledge on quantitation using MRI. Now, more than a decade later, it was due time for an update on this rapidly developing field, and the second edition by Cercignani, Dowell, and Tofts will surely become as popular.The chapters are written by international experts in the field cover the whole scope of qMRI techniques to study the human brain. The extended chapter on quality assurance is particularly instructive to medical physics experts.The chapters on the philosophical groundwork of the principles of physical measurement have been thoroughly extended, making it a must read for students entering the field of qMRI and an inspiration for reflections of senior researchers. I am using the second edition extensively for teaching students."

Dr. Gunther Helms, Senior lecturer, Swedish National 7T Facility, Lund University, Sweden

"'Quantitative MRI of the Brain', edited by Cercignani, Dowell and Tofts, is a comprehensive and authoritative reference for this important area of research, which is rapidly developing with novel scanning techniques and increasing interest in microstructure imaging.
The book provides an accessible introduction for those new to the field, while offering advanced readers sufficient detail on the broad variety of quantification approaches in anatomical and physiological imaging. The discussion of each quantitative parameter and technique is well balanced to cover theory, technical aspects, biological interpretation, and applications. This second edition of 'Quantitative MRI of the Brain', a substantial and timely revision, promises to become a classic as its predecessor already is."
Prof. Dr. Nikolaus Weiskopf, Director of Department of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Germany

Author preprints for download

The first edition:
Quantitative MRI of the brain: measuring changes caused by disease.

edited by Paul Tofts    hardback:  ISBN: 0470847212      paperback: ISBN 0470014296     published by John Wiley  2003

 Winner of 2004 British Medical Association radiology book prize click here        contents

ALL REVIEWS  - none left out!  NMR in Biomedicine 2004  (pdf file)          Institute of Physics and Engineering in Medicine (UK) 2004      Journal of Neurology Neurosurgery and Psychiatry 2004    
 Rad Magazine June 2004     
   British Medical Association 2004        British Journal of Radiology 2005    BJR pdf   

Standards in Quantitative MR list serve:   http://ismrm.org/sqmr/sqmrrules.htm
Overview of qMR - revision in progress.

this is based on the book chapters of the first edition, and will be expanded to include summaries and links to more recent information:
1. Concepts: Measurement and MR
2. The Measurement Process: MR Data Collection and Image Analysis
3. QA: Quality Assurance, Accuracy, Precision and Phantoms
4. PD: Proton Density of Tissue Water
5. T1: the Longitudinal Relaxation Time
6. T2: the Transverse Relaxation Time
7. D: the Diffusion of Water
8. MT: Magnetisation Transfer
9. Spectroscopy: 1H Metabolite Concentrations
10. T1-w DCE-MRI: T1-weighted Dynamic Contrast-enhanced MRI
   Teorell T. Kinetics of distribution of substances administered to the body.
        I. The extravascular modes of administration.
Arch Int Pharmacodyn et Ther 1937;57:205-225.  download
       2. The intravascular modes of administration. Arch Int Pharmacodyn et Ther 1937;57:226-240. download
11. T2- and T2*-w DCE-MRI: Blood Perfusion and Volume Estimation using Bolus Tracking
12. Functional MRI
13. ASL: Blood Perfusion Measurements using Arterial Spin Labelling
14. Biology: The Significance of MR Parameters in Multiple Sclerosis
15. Spatial Registration of Images
16. Volume and Atrophy
17. Shape and Texture
18. Histograms: Measuring Subtle Diffuse Disease          more on histograms


last updated: Sepember 20th 2018;   qmri.org     domain owner: Paul Tofts